You are hereLaboratory of cell and developmental biology of photosynthetic organisms

Laboratory of cell and developmental biology of photosynthetic organisms

Csaba Máthé associate professor
Márta Mikóné Hamvas senior lecturer
Gyula Surányi  senior lecturer

Tamás Garda PhD student
Anna Resetár PhD student

Fülöpné Barabás Éva assistant


Main research fields:

Regulation of plant subcellular dynamics and the role of protein phosphatases in these processes. Establishment of plant tissue cultures and their screening for secondary metabolite content. Cyanobacterial toxins as tools in the study of plant cytoskeleton and chromatin organization. Plant tissue- and cellular stress responses to cyanobacterial toxins. Metabolic changes induced by cyanobacterial toxins during the cyanophage cycle. The study of interaction between cyanophage infection and cyanotoxin production.

Research topics:
    The role of protein phosphatases in the regulation of cytoskeleton-driven subcellular dynamics. Model plants: Vicia faba, Arabidopsis.
    The study of plant cell death processes (PCD, necrosis) and ROS elevation induced by protein phosphatase and protein synthesis inhibitory cyanotoxins at tissue, cellular (chromatin, cytoskeleton) and biochemical (nucleases, proteases, transglutaminases, peroxidases, catalase) levels. Model systems are plants cultured in vitro: aquatic macrophytes (Lemna, Wolffia, Ceratophyllum, Phragmites) and Sinapis alba, V. faba, Arabidopsis.
    Tissue culture (mainly micropropagation and callus culture) of plants important for species conservation (Galanthus, Leucojum, Sternbergia species /Amaryllidaceae/; Crocus species /Iridaceae/). The study of their secondary metabolite content and antioxidant capacity. The study of genetic intactness of tissue cultures derived plants by DNA polymorphism (AFLP) methods.
    The effects of cyanotoxins on the regulation of cyanophage cycle at the cell and molecular levels. Studies of cyanobacterial host and phage cycle (protein synthesis / DNA changes) based on radioactive labelling and different PCR techniques.
    The study of DNA polymorphism (PCR-based/AFLP methods) of cyanobacteria.

Significant publications:

M. Hamvas, M., Máthé, Cs., Papp, M., Grigorszky, I., Molnár, E., Vasas, G., Borbély, Gy. (2003) Microcystin-LR alters growth, anthocyanin content and single-stranded DNase enzyme activities in Sinapis alba L. seedlings. Aquat. Toxicol. 62:1-9

Máthé, Cs., M-Hamvas, M., Vasas, G., Surányi, Gy., Bácsi, I., Beyer, D., Tóth, Sz., Tímár, M., Borbély, G. (2007) Microcystin-LR, a cyanobacterial toxin, induces growth inhibition and histological alterations in common reed (Phragmites australis /Cav./ Trin. Ex Steud.) plants regenerated from embryogenic calli. New Phytol. 176: 824-835

Demeter, Z., Surányi, G., Molnár, V.A., Sramkó, G., Beyer, D., Kónya, Z., Vasas, G., M-Hamvas, M., Máthé, C. (2010) Somatic embryogenesis and regeneration from shoot primordia of Crocus heuffelianus. Plant Cell Tiss. Org. 100: 349-353

Beyer, D., Tándor, I., Kónya, Z., Bátori, R., Roszik, J., Vereb, G., Erdődi, F., Vasas, G., M-Hamvas, M., Jambrovics, K., Máthé, C. (2012) Microcystin-LR, a protein phosphatase inhibitor induces alterations in mitotic chromatin and microtubule organization leading to the formation of micronuclei in Vicia faba. Ann. Bot. 110: 797-808

Máthé C., M-Hamvas M.,Vasas G. (2013) Microcystin-LR and cylindrospermopsin induced alterations in chromatin organization of plant cells. Mar. Drugs 168: 3689-3717